How Unequal Vaccine Distribution Promotes the Evolution of Vaccine Escape
نویسندگان
چکیده
منابع مشابه
Vaccine escape in 2013-4 and the hydropathic evolution of glycoproteins of A/H3N2 viruses
EXCODD More virulent strains of influenza virus subtypes H1N1 appeared widely in 2007 and H3N2 in 2011, and especially 2013-4, when the effectiveness of the H3N2 vaccine decreased nearly to zero. The amino acid differences of neuraminidase from prior less virulent strains appear to be small (<1%) when tabulated through sequence alignments and counting site identities and similarities. Here we s...
متن کاملEvidence for Soft Selective Sweeps in the Evolution of Pneumococcal Multidrug Resistance and Vaccine Escape
The multidrug-resistant Streptococcus pneumoniae Taiwan(19F)-14, or PMEN14, clone was first observed with a 19F serotype, which is targeted by the heptavalent polysaccharide conjugate vaccine (PCV7). However, "vaccine escape" PMEN14 isolates with a 19A serotype became an increasingly important cause of disease post-PCV7. Whole genome sequencing was used to characterize the recent evolution of 1...
متن کاملThe Evolution of the Meningitis Vaccine Project
BACKGROUND In 2001, the Meningitis Vaccine Project (MVP) was tasked to develop, test, license, and introduce a group A meningococcal (MenA) conjugate vaccine for sub-Saharan Africa. African public health officials emphasized that a vaccine price of less than US$0.50 per dose was necessary to ensure introduction and sustained use of this new vaccine. METHODS Initially, MVP envisioned partnerin...
متن کاملGlobal Coverage of Pneumococcal Conjugate Vaccine (PCV) and Serotype Distribution after Receiving Vaccine among Targeted PCV Vaccine Countries: A Systematic Review
Background and Objectives: After the introduction of the pneumococcal vaccine, an increase has been observed in the disease due to nonspecific stereotypes of the vaccine. This study was conducted to determine the spatial distribution of pneumococcal vaccine coverage and common stereotypes of streptococcus pneumonia after vaccine introduction in the vaccine recipient countries. Methods: The ...
متن کاملThe Predictive Role of Vaccine Literacy and Vaccine Hesitancy on Acceptance of COVID-19 Vaccination
Background: Vaccination is preventive behavior, and vaccine literacy and hesitancy appear to influence vaccination. The aim of this study was to determine the role of vaccine literacy and hesitancy on the acceptance of the COVID-19 vaccine. Materials and Methods: In this cross-sectional study, 2185 residents over 18 years old in urban and rural health centers in three cities of Dashtestan, Dash...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: SSRN Electronic Journal
سال: 2021
ISSN: 1556-5068
DOI: 10.2139/ssrn.3827009